British Journal of Oral and Maxillofacial Surgery
Volume 45, Issue 5 , Pages 372-377 , July 2007

Specific expression of substance P in synovial tissues of patients with symptomatic, non-reducing internal derangement of the temporomandibular joint: Comparison with clinical findings

  • Jun Sato

      Affiliations

    • Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
    • Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine, North 13, West 7, Kita-ward, Sapporo City 060-8586, Japan
    • Corresponding Author InformationCorresponding author at: Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine, North 13, West 7, Kita-ward. Sapporo City 060-8586, Japan. Tel.: +81 11 716 2111; fax: +81 11 706 4280.
    • ,
  • Natsuki Segami

      Affiliations

    • Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
    • ,
  • Yoshino Yoshitake

      Affiliations

    • Department of Biochemistry, Kanazawa Medical University, Japan
    • ,
  • Keiseki Kaneyama

      Affiliations

    • Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
    • ,
  • Hiroshi Yoshimura

      Affiliations

    • Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
    • ,
  • Kazuma Fujimura

      Affiliations

    • Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan
    • ,
  • Yoshimasa Kitagawa

      Affiliations

    • Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine, North 13, West 7, Kita-ward, Sapporo City 060-8586, Japan

,Accepted 21 September 2006.

References 

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  16. Sato J, Segami N, Nishimura M, et al. Expression of interleukin 6 in synovial tissues in patients with internal derangement of the temporomandibular joint. Br J Oral Maxillofac Surg. 2003;41:95–101
  17. Mapp PI, Kidd BL, Gibson SJ, et al. Substance P-, calcitonin gene-related peptide- and C-flanking peptide of neuropeptide Y-immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritis. Neuroscience. 1990;37:143–153
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  19. Holmlund A, Ekblom A, Hansson P, Lind J, Lundeberg T, Theodorsson E. Concentrations of neuropeptides substance P, neurokinin A, calcitonin gene-related peptide, neuropeptide Y and vasoactive intestinal polypeptide in synovial fluid of the human temporomandibular joint. A correlation with symptoms, signs, and arthroscopic findings. Int J Oral Maxillofac Surg. 1991;20:228–231
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  21. Walsh DA, Mapp PI, Wharton J, et al. Localisation and characterisation of substance P binding to human synovial tissue in rheumatoid arthritis. Ann Rheum Dis. 1992;51:313–317
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  23. Lotz M, Carson DA, Vaughan JH. Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis. Science. 1987;235:893–895
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PII: S0266-4356(06)00184-7

doi: 10.1016/j.bjoms.2006.09.011

British Journal of Oral and Maxillofacial Surgery
Volume 45, Issue 5 , Pages 372-377 , July 2007

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