British Journal of Oral and Maxillofacial Surgery
Volume 46, Issue 1 , Pages 15-21, January 2008

Oral mucosal disease: Lichen planus

  • Crispian Scully

      Affiliations

    • University College London, Eastman Dental Institute, UK
    • Corresponding Author InformationCorresponding author at: Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WC1X 8LD, UK. Tel.: +44 20 7915 1038; fax: +44 20 7915 1039.
  • ,
  • Marco Carrozzo

      Affiliations

    • University of Newcastle, UK

Accepted 19 July 2007. published online 06 September 2007.

Abstract 

Lichen planus (LP) is a common disorder in which auto-cytotoxic T lymphocytes trigger apoptosis of epithelial cells leading to chronic inflammation. Oral LP (OLP) can be a source of severe morbidity and has a small potential to be malignant.

The diagnosis of OLP can be made from the clinical features if they are sufficiently characteristic, particularly if typical skin or other lesions are present, but biopsy is recommended to confirm the diagnosis and to exclude dysplasia and malignancy.

OLP is treated with anti-inflammatory agents, mainly the topical corticosteroids, but newer agents and techniques are becoming available.

Keywords: Lichen planus, Oral, Skin

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PII: S0266-4356(07)00372-5

doi:10.1016/j.bjoms.2007.07.199

British Journal of Oral and Maxillofacial Surgery
Volume 46, Issue 1 , Pages 15-21, January 2008