British Journal of Oral and Maxillofacial Surgery
Volume 46, Issue 6 , Pages 455-459 , September 2008

Effect of betamethasone on the degree of macrophage recruitment and nerve growth factor receptor p75 immunoreaction during recovery of the sciatic nerve after injury: an experimental study in rats

  • Awwad Al-Bishri

      Affiliations

    • Department of Oral and Maxillofacial Surgery, Al-Noor Specialist Hospital, Makkah, Saudi Arabia
    • Corresponding Author InformationCorresponding author.
  • ,
  • Sture Forsgren

      Affiliations

    • Department of Integrative Medical Biology, Faculty of Medicine, Umeå University
  • ,
  • Yasser Al-Thobaiti

      Affiliations

    • Department of Oral and Maxillofacial Surgery, University Hospital MAS, Malmö University, Malmö, Sweden
  • ,
  • Bo Sunzel

      Affiliations

    • Department of Oral and Maxillofacial Surgery, University Hospital MAS, Malmö University, Malmö, Sweden
  • ,
  • Jan Rosenquist

      Affiliations

    • Department of Oral and Maxillofacial Surgery, University Hospital MAS, Malmö University, Malmö, Sweden

,Accepted 31 January 2008.

References 

  1. Waller A. Experiments on the section of the glossopharyngeal and hypoglossal nerves of the frog and observations of the alterations produced thereby in the structure of their primitive fibers. Phil Trans R Soc Lond (Biol). 1850;140:423–429
  2. Dahlin LB, Miyauchi A, Thomsen P, Danielsen N, Kanje M. Stimulation of nerve regeneration by macrophages in granulation tissue. Rest Neurol Neurosci. 1996;9:141–149
  3. Dailey AT, Avellino AM, Benthem L, Silver J, Kliot M. Complement depletion reduces macrophages infiltration and activation during Wallerian degeneration and axonal regeneration. J Neurosci. 1998;18:6713–6722
  4. Miyauchi A, Kanje M, Danielsen N, Dahlin LB. Role of macrophages in the stimulation and regeneration of sensory nerve by transposed granulation tissue and temporal aspects of the response. Scand J Plast Reconstr Surg Hand Surg. 1997;31:17–23
  5. Dahlin LB. Prevention of macrophage invasion impairs regeneration in nerve grafts.. Brain Res. 1995;679:274–280
  6. Liefner M, Siebert H, Sachse T, Michel U, Kollias G, Brück W. The role of TNF during Wallerian degeneration. J Neuroimmunol. 2000;108:147–152
  7. Schimmer BP, Parker KL. Adrenocorticotropic hormone; Adrenocortical steroids and their synthetic analogs; Inhibitors of the synthesis and actions of adrenocortical hormones. In:  Hardman JG,  Limbird LE, et al. editor. Goodman and Gilman's pharmacological basis of therapeutics. 9th ed.. New York: McGraw-Hill; 1996;
  8. Al-Bishri A, Dahlin L, Rosenquist J, Sunzel B. On neurosensory disturbance after sagittal split osteotomy. J Oral Maxillofac Surg. 2004;62:1472–1476
  9. Chiou WL, Robbie G, Chung AM, Wu TC, Ma C. Correlation of plasma clearance of 54 extensively metabolized drugs between human and rats: Mean allometric coefficient of 0.66. Pharmaceutical Research. 1998;15:1474–1479
  10. Al-Bishri A, Dahlin L, Sunzel B, Rosenquist J. Systemic betamethasone accelerates functional recovery after a crush injury to rat sciatic nerve. J Oral Maxillofac Surg. 2005;63:973–977
  11. Lee CMY, Kumar RK, Lubowski DZ, Burcher E. Neuropeptides and nerve growth in inflammatory bowel disease: a quantitative immunohistochemical study. Dig Dis Sci. 2002;47:495–502
  12. Ibanez CF. Emerging themes in structural biology of neurotrophic factors. Trends Neurosci. 1998;21:438–444
  13. Levi-Montalcini R, Skaper SD, Dal Toso R, Petrelli L, Leon A. Nerve growth factor: from neurotrophin to neurokine. Trends Neurosci. 1996;19:514–520
  14. Chao MV, Hempstead BL. p75 and Trk: a two-receptor system. Trends Neurosci. 1995;18:321–326
  15. Klein R, Nanduri V, Jing SA, et al. The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell. 1991;66:395–403
  16. Ernfors P. Local and target-derived actions of neurotrophins during peripheral nervous system development. Cellular and Molecular Life Sciences. 2001;58:1036–1044
  17. Fu SY, Gordon T. The cellular and molecular basis of peripheral nerve regeneration. Mol Neurobiol. 1997;14:67–116
  18. Ribeiro-da-Silva A, Kenigsberg RL, Cuello AC. Light and electron microscopic distribution of nerve growth factor receptor-like immunoreactivity in the skin of the rat lower lip. Neurosci. 1991;43:631–646
  19. Liang Y, Marcusson J, Johansson O. Light and electron microscopic immunohistochemical observations of p75 nerve growth factor receptor-immunoreactive dermal nerves in prurigo nodularis. Arch Dermatol Res. 1999;291:14–21
  20. Thomson TM, Rettig WJ, Chesa PG, Green SH, Mena AC, Old LJ. Expression of human nerve growth factor receptor on cells derived from all three germ layers. Exp Cell Res. 1988;174:533–539
  21. Alonso G. Prolonged corticosterone treatment of adult rats inhibits the proliferation of oligodendrocyte progenitors present throughout white and gray matter regions of the brain. GLIA. 2000;31:219–231
  22. Nasser RM, Chen LE, Seaber AV, Urbaniak JR. Protective effect of 21-aminosteroid pretreatment in peripheral nerve low-load crush injury in mature and immature rats. J Orthop Res. 1996;14:823–829
  23. Bracken MB, Shepard MJ, Collins WF, et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal cord injury (result of the second National Acute Spinal Cord Injury Study). N Engl J Med. 1990;322:1405–1411
  24. Rabchevsky AG, Fugaccia I, Sullivan PG, Blades DA, Scheff SW. Efficacy of methylprednisolone therapy for the injured rat spinal cord. J Neurosci Res. 2002;68:7–18
  25. Stoll G, Müller HW. Nerve injury, axonal degeneration and neural regeneration: Basic insight. Brain Path. 1999;9:313–325

PII: S0266-4356(08)00096-X

doi: 10.1016/j.bjoms.2008.01.020

British Journal of Oral and Maxillofacial Surgery
Volume 46, Issue 6 , Pages 455-459 , September 2008