Clinical and histopathological analysis of oral squamous cell carcinoma in young people: A descriptive study in Brazilians

Ribeiro, Ana Carolina Prado; Silva, Alan Roger Santos; Simonato, Luciana Estevam; Salzedas, Leda Maria Pescinini; Sundefeld, Maria Lucia Marçal Mazza; Soubhia, Ana Maria Pires

doi:10.1016/j.bjoms.2008.05.004

« Previous Next »British Journal of Oral and Maxillofacial Surgery
Volume 47, Issue 2 , Pages 95-98, March 2009

Clinical and histopathological analysis of oral squamous cell carcinoma in young people:

A descriptive study in Brazilians

Ana Carolina Prado Ribeiro
- Department of Pathology and Clinical Propedeutics (Oral Pathology), São Paulo State University - UNESP, Araçatuba, São Paulo, Brazil
- Corresponding author. Faculdade de Odontologia de Araçatuba- UNESP. Departamento de Patologia e Propedêutica Clínica. Rua José Bonifácio, 1193, Caixa Postal 261, Araçatuba -SP, Brasil CEP: 16015-050. Tel.: +55 18 36363312; fax: +55 18 36363332.
Alan Roger Santos Silva
- Department of Oral Diagnosis (Semiology), Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil
Luciana Estevam Simonato
- Department of Pathology and Clinical Propedeutics (Oral Pathology), São Paulo State University - UNESP, Araçatuba, São Paulo, Brazil
Leda Maria Pescinini Salzedas
- Department of Pathology and Clinical Propedeutics (Oral Pathology), São Paulo State University - UNESP, Araçatuba, São Paulo, Brazil
Maria Lucia Marçal Mazza Sundefeld
- Department of Infantile and Social Dentistry - São Paulo State University - UNESP, Araçatuba, São Paulo, Brazil
Ana Maria Pires Soubhia
- Department of Pathology and Clinical Propedeutics (Oral Pathology), São Paulo State University - UNESP, Araçatuba, São Paulo, Brazil

Accepted 13 May 2008. published online 01 July 2008.

Abstract

We retrospectively analysed the clinical and histological characteristics of oral squamous cell carcinoma (SCC) in a sample of Brazilian patients 45 years of age or less. Files from a single oral histopathological service were studied during the period 1990 to 2005 and the clinical data collected. The histological sections of the invasive part of each tumour were analysed and classified using the criteria of Bryne et al. A total of 46 patients were selected, 36 (78%) of whom were white; 38 (83%) were male; and the most common site was the floor of the mouth (n=14, 30%) followed by the tongue (n=13, 28%). Most selected patients used tobacco and alcohol, and 43 were diagnosed as having clinical stages III and IV disease. Nine of the tumours (20%) were well differentiated, 23 were moderately differentiated, and the rest (n=14) were poorly differentiated. The characteristics of this group suggest that oral SCC in young patients does not behave differently from the oral SCC found in the overall population.