British Journal of Oral and Maxillofacial Surgery
Volume 47, Issue 4 , Pages 294-297, June 2009

Bisphosphonate osteonecrosis: a protocol for surgical management

  • George Markose

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +44 1563 577296; fax: +44 1563 577300.
  • ,
  • Fiona R. Mackenzie

      Affiliations

    • Tel.: +44 1563 577296; fax: +44 1563 577300.
  • ,
  • W.J.R. Currie

      Affiliations

    • Tel.: +44 1563 577293; fax: +44 1563 577300.
  • ,
  • W.S. Hislop

      Affiliations

    • Tel.: +44 1563 577288; fax: +44 1563 577300.

Dept. of Oral & Maxillofacial Surgery, Crosshouse Hospital, Kilmarnock, Ayrshire KA2 0BE, UK

Accepted 9 January 2009. published online 24 February 2009.

Abstract 

We present a protocol for the management of a subgroup of patients with bisphosphonate osteonecrosis who presented with painful, exposed, necrotic, alveolar bone. It is simple and can easily be adapted to suit anatomical variations of the oral cavity. Current guidelines based on consensus for the management of bisphosphonate-induced osteonecrosis fail to provide mucosal coverage, which is a primary requirement in managing the condition. We have evaluated the results of a group of 15 patients and analysed their postoperative progress for 24 months.

Keywords: Bisphosphonate, Osteonecrosis, Surgical management

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PII: S0266-4356(09)00028-X

doi:10.1016/j.bjoms.2009.01.007

British Journal of Oral and Maxillofacial Surgery
Volume 47, Issue 4 , Pages 294-297, June 2009