Abstract
The purpose of this retrospective study was to assess the effect of vital staining
with iodine solution in reducing local recurrence after resection of dysplastic or
malignant oral mucosa. The historical control group had dysplastic or malignant mucosal
lesions resected solely on the evidence of direct inspection and palpation. In the
vital staining group tissue was resected only after vital staining with iodine solution.
Seven of 25 patients in the conventional group developed recurrent dysplastic or cancerous
oral mucosa around the primary site, while no patient among 23 reported recurrence
in the vital staining group (p < 0.01). Kaplan–Meier assessment showed that the 5-year primary control rate was 100%
in the vital staining group and 75% in the conventional group. Although this retrospective
study has some limitations, the results suggest that vital staining with iodine may
be useful in reducing the incidence of recurrence of dysplastic or cancerous epithelium
at a primary site. Further well-controlled study is essential.
Keywords
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Article info
Publication history
Published online: April 25, 2011
Accepted:
March 26,
2011
Identification
Copyright
© 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
