Abstract
Rhabdomyosarcoma (RMS) is the most common malignant soft tissue tumour of childhood
and has two main subtypes: embryonal and alveolar. The embryonal subtype accounts
for most cases in the genitourinary tract and head and neck. Oral presentations are
rare, and mainly in the tongue, palate, or cheek. Cytogenetically, alveolar RMS is
characterised by the translocation t(2;13)(q35;q14), which plays an important part
in diagnosis, but no consistent and unique genetic alterations have been identified
in embryonal RMS. It is currently not known whether oral embryonal RMS is similar
to those that arise from other sites, as only one cytogenetic report has been published
to date. We present the case of a 9-year-old boy with embryonal RMS of the cheek,
and discuss the cytogenetic alterations in his case.
Keywords
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Article info
Publication history
Published online: January 27, 2012
Accepted:
December 31,
2011
Identification
Copyright
© 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
