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Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management

Published:October 29, 2012DOI:https://doi.org/10.1016/j.bjoms.2012.08.014

      Abstract

      Oral submucous fibrosis (OSMF) is a complex, debilitating, and precancerous condition. Formerly confined to the Indian subcontinent, it is now often seen in the Asian populations of the United Kingdom, USA, and other developed countries, and is therefore a serious problem for global health. The well-known causative agent of the disease, areca-nut is now recognised as a group one carcinogen. We review and discuss all components of OSMF, including the terminology, presentation, aetiology, and pathogenesis, and provide a brief overview of its management.

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