Abstract
We know of only limited data about the role of oral hygiene and the risk of oral cancer
with different standards of education. The aim of this study was to assess the association
between oral hygiene and risk of oral cancer, with stratification by standard of education,
in Chinese women. We organised a case-control study with 250 women with oral cancer
and 996 age-matched controls in Fujian, China. Data were collected by personal interview
using a structured questionnaire. We used unconditional logistic regression with stratification
by educational standard to estimate the odds ratios (OR) and 95% CI. Tooth-brushing
twice a day or more was inversely related to the risk of oral cancer in women with
high school education or above (OR 0.50; 95% CI 0.25 to 0.98), but not in those who
were illiterate or had primary-middle school education. Wearing dentures showed an
increased risk only in less well-educated women: the OR were 2.23 (95% CI 1.14 to
4.34) for the illiterate and 1.68 (95% CI 1.08 to 2.62) for the primary-middle school
group. The loss of more than five teeth and oral ulceration were associated with increased
risks of oral cancer in all three groups. There was also a multiplicative interaction
between oral hygiene and standard of education for risk of oral cancer (p = 0.001). Our results suggest that oral hygiene seems to have a critical role in the
risk of oral cancer in Chinese women, but this effect may be modified by their educational
standard.
Keywords
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Article info
Publication history
Published online: November 28, 2016
Accepted:
November 15,
2016
Identification
Copyright
© 2016 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
