Abstract
Signet-ring cell (histocytoid) carcinoma is a rare and aggressive skin neoplasm that
most commonly affects elderly men. It typically originates from the upper or lower
eyelid, with bilateral involvement only in rare cases, and results in a diffuse and
infiltrative appearance clinically, radiologically, and histologically (the “monocle”
sign). It is essential to carry out a full investigation to rule out metastasis from
an internal origin.
Keywords
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References
- Signet-ring cell/histiocytoid carcinoma of the eyelid: a case report and review of the literature.Am J Dermatopathol. 2013; 35: e1-e5
- Primary signet-ring cell/histiocytoid carcinoma of the eyelid: a "binocle" presentation of the “monocle tumor”.Am J Dermatopathol. 2016; 38: 623-627
- Primary signet-ring cell/histiocytoid carcinoma of the eyelid: a clinicopathologic study of 5 cases and review of the literature.Am J Surg Pathol. 2011; 35: 378-391
- Signet ring cell carcinoma of the eyelid — the monocle tumour.APMIS. 2008; 116: 326-332
- A case of primary signet-ring cell/histiocytoid carcinoma of the eyelid: immunohistochemical comparison with the normal sweat gland and review of the literature.Am J Dermatopathol. 2012; 34: 139-145
- Pulmonary signet-ring cell adenocarcinoma metastatic to the skin.Am J Dermatopathol. 2017; 39: e66-8
- Primary signet-ring cell/histiocytoid carcinoma of the eyelid expressing androgen receptors and treated with bicalutamide.J Dermatol. 2017; 44: e230-e231
Article info
Publication history
Published online: February 06, 2020
Identification
Copyright
Crown Copyright © 2020 Published by Elsevier Ltd on behalf of The British Association of Oral and Maxillofacial Surgeons. All rights reserved.
