Abstract
Medication-related osteonecrosis of the jaws (MRONJ) is a rare complication of bisphosphonates,
or antiresorptive or antiangiogenic medication. Treatment is difficult as the bone
has a poor capacity for healing, and further progression after surgery can occur.
Quality of life (QoL) in patients with MRONJ has not been well documented. The aim
of this study therefore was to identify and analyse data on QoL in this group of patients.
Eight studies that were identified through a systematic search of the literature were
qualitatively analysed. Overall, data on QoL are lacking and are complicated by concurrent
disease such as cancer. Patients generally have a poor QoL because of MRONJ, and multiple
oral-specific complaints including pain and problems with speech. Development of a
questionnaire specific to patients with MRONJ would help improve the specificity of
the data collected. Prospective questionnaires before and after intervention, including
information on stage and comorbidities, would guide future treatment strategies.
Keywords
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Article info
Publication history
Published online: April 01, 2020
Accepted:
March 10,
2020
Identification
Copyright
© 2020 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
