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Comparing donor site morbidity between radial and ulnar forearm free flaps: a meta-analysis

  • Qiang Xu
    Affiliations
    Department of Oral Maxillofacial Surgery, China

    School and Hospital of Stomatology Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, China
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  • Peng-Li Chen
    Affiliations
    Department of Pediatric Dentistry, China

    Shenzhen University General Hospital, Shenzhen, Guangdong Province 518000, China
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  • Yi-Hao Liu
    Affiliations
    Department of Oral Maxillofacial Surgery, China

    School and Hospital of Stomatology, China Medical University, Liaoning Province Key Laboratory of Oral Diseases, Shenyang, Liaoning Province 110002, China
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  • Si-Min Wang
    Affiliations
    Department of Oral Maxillofacial Surgery, China

    School and Hospital of Stomatology, China Medical University, Liaoning Province Key Laboratory of Oral Diseases, Shenyang, Liaoning Province 110002, China
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  • Zhong-Fei Xu
    Correspondence
    Corresponding authors at: Address: No. 117. Nanjing North Street, Heping District, Shenyang, Liaoning 110002, PR China.
    Affiliations
    Department of Oral Maxillofacial Surgery, China

    School and Hospital of Stomatology, China Medical University, Liaoning Province Key Laboratory of Oral Diseases, Shenyang, Liaoning Province 110002, China
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  • Cui-Juan Feng
    Correspondence
    Corresponding authors at: Address: No. 117. Nanjing North Street, Heping District, Shenyang, Liaoning 110002, PR China.
    Affiliations
    Department of Orthodontics, China

    School and Hospital of Stomatology, China Medical University, Liaoning Province Key Laboratory of Oral Diseases, Shenyang, Liaoning Province 110002, China
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Published:November 09, 2021DOI:https://doi.org/10.1016/j.bjoms.2021.10.014

      Abstract

      The vascularised forearm free flap is a workhorse flap for the reconstruction of many types of soft tissue defects. However, the difference in donor-site morbidity between the radial forearm free flap (RFFF) and ulnar forearm free flap (UFFF) remains controversial. This study aimed to compare the donor-site outcomes of RFFF and UFFF. We searched PubMed, EMBASE, Web of Science, clinicaltrials.gov, Cochrane Library, and Chinese Biomedical Literature Database up to August 10, 2021, to identify studies on donor-site outcomes of RFFF versus UFFF in patients undergoing reconstructive surgery. Two authors individually extracted data and performed quality assessments of the selected articles. The overall morbidity and overall effect of individual complications of the donor site were analysed. In total, 288 cases from five studies were included in our analysis. The UFFF group was significantly superior to the RFFF group regarding overall morbidity and overall effect of individual complications of the donor site. The morbidity of UFFF donor sites was significantly lower than that of RFFF, and UFFF may be an ideal substitute for RFFF in reconstructive surgery. However, additional large-scale studies are necessary to confirm this finding.

      Keywords

      Abbreviations:

      RFFF (radialforearmfreeflap), UFFF (ulnar forearm free flap), PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), CBM (Chinese Biomedical Literature Database), RR (relative risk), CI (confidence interval), MH (Mantel-Haenszel), DL (DerSimonian and Laird)
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