Abstract
Patients undergoing sentinel node biopsy (SLNB) for early oral squamous cell carcinoma
(OSCC) who harbour occult metastases (pN+ve) may be at greater risk of mortality due
to prolonged overall treatment times than those identified as pN+ve on elective neck
dissection (ELND). A retrospective comparative survival analysis was therefore undertaken
to test this hypothesis. Patients were identified from the South Glasgow multidisciplinary
team (MDT) database. Group 1 comprised 38 patients identified as pN+ve, or who were
false negative, on sentinel lymph node biopsy (SLNB). Group 2 comprised 146 patients
staged pN+ve on ELND. The groups were compared with the Kaplan Meier method and Cox
proportional hazards model. In addition, a matched-pair analysis was performed. A
unique and specifically designed algorithm was deployed to optimise the pairings.
No difference in disease-specific or overall survival was found between the groups.
Patients undergoing SLNB as the initial neck staging modality in early OSCC and are
identified as pN+ve do not appear to be at a survival disadvantage compared with those
staged with ELND.
Keywords
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Article Info
Publication History
Published online: March 09, 2022
Accepted:
January 12,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
Crown Copyright © 2022 Published by Elsevier Ltd on behalf of The British Association of Oral and Maxillofacial Surgeons. All rights reserved.
