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Corrigendum to “Blindness associated with platelet-rich plasma temporomandibular joint injections” [Br. J. Oral Maxillofac. Surg. 58(9) (2020) 1197–1199]

      The authors regret to inform that the blindness by embolisation was caused by activated mesenchymal pericyte plasma injections, which is also known as LIpgems© rather than ‘Platelet-rish plasma’ injection. In the original publication, the authors found only one previous ‘Platelet-rich plasma’ injection associated blindness however, in the case of LIpgems© there was no evidence whatsoever in the literature. Despite the change in the type of the treatment the patient received, the case report maintains its rarity and learning point of disclosing visual loss as a rare complication of any temporomandibular injection.
      The authors would like to remove:
      ‘Platelet-rich plasma (PRP) is an autologous product composed of growth factors that can be up to 8 times the level in normal blood. Studies have shown it to be more clinically and radiologically efficacious when compared to other forms of intraarticular injections like steroids and Hyaluronic acid (HA)’.
      The authors would like to add:
      ‘Mesenchymal pericyte plasma injections can be harvested from subcutaneous fat tissues, and this source often gives patients the opportunity to have 500 times more stem cells than bone marrow extracted stem cells.
      • Surowiecka A.
      • Strużyna J.
      Adipose-Derived Stem Cells for Facial Rejuvenation.
      Activated mesenchymal pericyte plasma injections have already been used for osteoarthritis where significant therapeutic evidence has been well documented in the literature.
      • Lopa S.
      • Colombini A.
      • Moretti M.
      • de Girolamo L.
      Injective mesenchymal stem cell-based treatments for knee osteoarthritis: from mechanisms of action to current clinical evidences.
      The authors would like to apologise for any inconvenience caused.

      References

        • Surowiecka A.
        • Strużyna J.
        Adipose-Derived Stem Cells for Facial Rejuvenation.
        J Pers Med. 2022; 12: 117
        • Lopa S.
        • Colombini A.
        • Moretti M.
        • de Girolamo L.
        Injective mesenchymal stem cell-based treatments for knee osteoarthritis: from mechanisms of action to current clinical evidences.
        Knee Surg Sport Traumatol Arthrosc. 2019; 27: 2003-2020https://doi.org/10.1007/s00167-018-5118-9

      Linked Article

      • Blindness associated with platelet-rich plasma temporomandibular joint injections
        British Journal of Oral and Maxillofacial SurgeryVol. 58Issue 9
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          This case report highlights an ocular complication associated with platelet-rich plasma temporomandibular joint injections. This pioneering treatment can risk irreversible visual loss. This case highlights the importance of an experienced technique, in depth understanding of facial anatomy, and promptly recognising and referring the patient to a specialist to manage the complication should it arise.
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