Abstract
Severe pain experienced by patients with oral submucous fibrosis (OSMF) compromises
their physiotherapy and negatively affects the surgical outcome and the patient’s
compliance. The main aim of this study was to develop a protocol for pain control
in the management of OSMF postoperatively. This was a prospective, parallel with active
control, double-arm, triple-blinded, randomised control trial (RCT) with 48 OSMF patients,
randomised into two groups - Group A (control, n = 25): received non-opioid analgesics (NSAIDs) and Group B (cases, n = 23): received transdermal fentanyl patches (TFP). Pain and interincisal opening
were measured on postoperative days 1, 3, 5, 7, 9, and 15, and on the1st and 3rd postoperative months. Quality of Life (QoL) was assessed preoperatively, on the 15th day postoperatively, and 3rd month postoperatively, and compliance was documented postoperatively on the 9th day. The transdermal fentanyl patch was found to have statistically significantly
more effect in controlling severe pain during active mouth opening exercises, and
thus significantly increased the patients’ compliance. Although there was increased
mouth opening and QoL in the fentanyl group, the differences were statistically insignificant.
Our study recommends the use of TFP for better pain control and compliance in postoperative
OSMF patients.
Keywords
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Article info
Publication history
Published online: July 21, 2022
Accepted:
July 11,
2022
Received in revised form:
April 17,
2022
Received:
March 2,
2021
Identification
Copyright
© 2022 Published by Elsevier Ltd on behalf of The British Association of Oral and Maxillofacial Surgeons.
