Advertisement

The relative propensity for regional metastasis in floor of mouth squamous cell carcinoma versus other oral cavity subsites

Published:August 02, 2022DOI:https://doi.org/10.1016/j.bjoms.2022.07.012

      Abstract

      There are previous papers suggesting that floor of mouth (FOM) oral squamous cell carcinomas (OSCC) metastasise earlier than other oral cavity subsites. This report further evaluates that hypothesis. Between February 2006 and December 2019, 825 patients underwent curative resection of OSCC. Data on nodal metastases and depth of invasion (DOI) of the primary tumour were collated. The relationship between tumour DOI and likelihood of nodal metastases was examined. A total of 203 patients had a FOM OSCC, 75 of which had nodal metastases. No difference was found in the incidence of, or correlation with DOI, and occurrence of regional metastases when FOM was compared to other OSCC subsites. We conclude that FOM OSCC has a similar regional metastatic propensity as other subsites in the oral cavity.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to British Journal of Oral and Maxillofacial Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Kyzas P.
        Management of the cN0 neck in early oral cancer: time to revise the guidance?.
        Br J Oral Maxillofac Surg. 2021; 59: 387-388
        • Vassiliou L.V.
        • Acero J.
        • Gulati A.
        • et al.
        Management of the clinically N0 neck in early-stage oral squamous cell carcinoma (OSCC). An EACMFS position paper.
        J Craniomaxillofac Surg. 2020; 48: 711-718
        • Mohit-Tabatabai M.A.
        • Sobel H.J.
        • Rush B.F.
        • et al.
        Relation of thickness of floor of mouth stage I and II cancers to regional metastasis.
        Am J Surg. 1986; 152: 351-353
        • Balasubramanian D.
        • Ebrahimi A.
        • Gupta R.
        • et al.
        Tumour thickness as a predictor of nodal metastases in oral cancer: comparison between tongue and floor of mouth subsites.
        Oral Oncol. 2014; 50: 1165-1168
        • D’Cruz A.K.
        • Vaish R.
        • Kapre N.
        • et al.
        Elective versus therapeutic neck dissection in node-negative oral cancer.
        N Eng J Med. 2015; 373: 521-529